File Name: oxygen saturation targets and outcomes in extremely preterm infants .zip
The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years.
SUPPORT investigators and publishing editors, heads of government study funding agencies, and many ethicists have argued that informed consent was adequate because the two oxygen saturation target ranges studied fell within a range commonly recommended in guidelines. Data were extracted on intended and achieved oxygen saturation levels as determined by pulse oximetry. Blinded targeting of a low narrow range resulted in significantly lower achieved oxygen saturations and a doubling of time spent below the lower limit of the intended range compared to usual care practices. Descriptions of major differences between the interventions studied and commonly practiced usual care, as well as potential risks associated with these differences, are essential elements of adequate informed consent. This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.
Recent clinical practice changes in neonatal care resulted in higher, narrower oxygen saturation target ranges for preterm infants. The effect of targeting higher or lower oxygen saturations on respiratory outcomes of preterm infants and duration of hospitalization has not been extensively reviewed in the context of current care, but could have significant implications. The primary outcome was bronchopulmonary dysplasia BPD. Secondary outcomes were evaluated with survival analysis and Wilcoxon rank sum test. The difference in duration of mechanical ventilation in the lower median 7. There were no statistically significant differences in the durations of other respiratory supports or hospital stay between the two groups.
Jump to navigation. Review question : Is it better to target a lower or higher level of oxygen for babies born very early? Background : Giving additional 'supplemental' oxygen to babies born very early 'extremely preterm infants' who have breathing difficulties has been common practice since the s.
Metrics details. FiO 2 -C is provided by commercially available and CE-marked ventilators with an FiO 2 -C algorithm intended for use in newborn infants. This will ensure an appropriate assessment of safety and efficacy before FiO 2 -C may be implemented as standard therapy.
The amount of oxygen given to preterm infants within the first few minutes of birth is one of the most contentious issues in modern neonatology. Just two decades ago, pure oxygen FiO 2 1. Due to concerns about oxidative stress and injury, clinicians rapidly adopted the practice of using less oxygen for the respiratory support of all infants, regardless of gestational maturity and pulmonary function. There is now evidence that initial starting fractional inspired oxygen may not be the only factor involved in providing optimum oxygenation and that the amount of oxygen given to babies within the first 10 min of life is a crucial factor in determining outcomes, including death and neurodevelopmental injury. In addition, evolving practice, such as non-invasive respiratory support and delayed cord clamping, need to be taken into consideration when considering oxygen delivery to preterm infants.
Мидж развела руками.
Даже через несколько часов после смерти лицо азиата отливало чуть розоватым загаром. Тело же его было бледно-желтого цвета - кроме крохотного красноватого кровоподтека прямо над сердцем. Скорее всего от искусственного дыхания и массажа сердца, - подумал Беккер. - Жаль, что бедняге это не помогло. Он принялся рассматривать руки покойного.
Начиная с того дня, анонимные переадресующие компании перестали быть для АНБ источником серьезных неприятностей.
Your email address will not be published. Required fields are marked *